Age-Related and Heteroplasmy-Related Variation in Human mtDNA Copy Number.

PLoS Genet · 2016 · PMC4792396 · PMID 26978189

Europe PMC DOI

hedged sentences

0.0020

closest p · 0.0× alpha

0.0490

boldest claim

The sentences

highly significantp≤0.002actually significant

SM exhibited a highly significant negative correlation between mtCN and the total number of heteroplasmies for all three methods (r = -0.27 to -0.31, all p≤0.002; Fig 4 and S4 Table ).

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borderline significantp = 0.049actually significant

MtCN was best explained by age (p<0.05), although the number of heteroplasmies also showed a slight correlation with mtCN that was borderline significant for shotgun sequencing data (p = 0.049, Fig 4 ).

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