Barely Significant
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Is MTHFR 677 C>T Polymorphism Clinically Important in Polycystic Ovarian Syndrome (PCOS)? A Case-Control Study, Meta-Analysis and Trial Sequential Analysis.

PLoS One · 2016 · PMC4794143 · PMID 26983014

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highly significantno p-value reported
Among all the studies pooled in this analysis, only one study on a Turkish population reported a highly significant association of 677C>T substitution with PCOS [ 18 ].

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.