In these brain areas, there was a highly significant dose relationship between increasing dietary exposure to l -BMAA and NFT density (Jonckheere–Terpstra trend test, Z -scores for the 14 brain regions range between 3.13 and 4.87, p < 0.001–0.00001; figure 3 ).
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Dietary exposure to an environmental toxin triggers neurofibrillary tangles and amyloid deposits in the brain.
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