Our study and that of Middeldorp et al 8 found different results for 8q23.3, 8q24.21 and 11q23.1 SNPs as, in the Dutch study, the association with 8q23.3 rs16892766 did not remain significant after correction for multiple testing, whereas the associations with the 8q24.21 and 11q23.1 at-risk alleles were highly significant.
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Clinical relevance of 8q23, 15q13 and 18q21 SNP genotyping to evaluate colorectal cancer risk.
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