Population pharmacokinetics of tanezumab in phase 3 clinical trials for osteoarthritis pain.

Br J Clin Pharmacol · 2016 · PMC4799925 · PMID 26613544

Europe PMC DOI

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highly significantno p-value reported

All of the relationships between covariates described above were highly significant due to the large number of subjects and observations, but WT had the largest influence in reducing IIV in CL from 35% to 27% with an estimated coefficient of 0.77.

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