Consistent superiority of selective serotonin reuptake inhibitors over placebo in reducing depressed mood in patients with major depression.

For the comparison-level analysis of all different effect parameters, Mauchly's test indicated the assumption of sphericity to be violated ( P <0.001); however, the P -value referring to the difference with respect to effect sizes (the within-cases factor) remained highly significant regardless of method of correction, the F-value being 47.4 ( P -value after Greenhouse-Geisser correction: <0.001).

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