Impact of Genotype on EPA and DHA Status and Responsiveness to Increased Intakes.

There is some earlier evidence of a borderline significant LDL-cholesterol raising effect of DHA in APOE4 carriers in those with modest hypertrigylceridaemia [ 71 ] which was not evident in later studies in normolipdaemic individuals [ 67 ] or using more moderate intervention doses [ 68 ].

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