Prognostic impact of programmed cell death-1 (PD-1) and PD-ligand 1 (PD-L1) expression in cancer cells and tumor-infiltrating lymphocytes in ovarian high grade serous carcinoma.

A partially significant effect was also seen in the subgroup without residual tumor after surgery (Agilent: p = 0.035, Figure 4C ; Affymetrix: p = 0.11, not shown; RNAseq: p = 0.19, not shown).

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Using this optimal cutoff, Kaplan-Meier analysis showed that CD3+ TILs had a significantly favorable impact on PFS and OS ( p = 0.001, p = 0.003), with borderline significance in multivariate analysis (Figure 2D ; Table 1 , Suppl.

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