Leukemia-associated activating mutation of Flt3 expands dendritic cells and alters T cell responses.

J Exp Med · 2016 · PMC4813676 · PMID 26903243

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highly significantno p-value reported

The effect of Flt3-ITD on DCs was allele dosage-dependent and was highly significant even in heterozygous Flt3 ITD/+ mice that appear normal otherwise.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.