The only study that examined the association between gender and BM was Barnholtz-Sloan et al., who reported a borderline significant higher incidence in male patients (1.9 %) than in female patients (1.7 %), but their study design did not make it possible to control for confounders [ 23 ].
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Systematic review: brain metastases from colorectal cancer--Incidence and patient characteristics.
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