In summary, both phase III trials failed to show prolongation of OS by BEV-containing treatment regimens, whereas significant and marginally significant PFS benefits were described, and contradicting results were obtained when evaluating quality of life or neurocognition (no data within the AVAglio trial), respectively [ 33 , 34 ].
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Bevacizumab and radiotherapy for the treatment of glioblastoma: brothers in arms or unholy alliance?
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