borderline significancep=0.007
Further multivariate analysis found that DM (hazard ratio [HR], 2.68; 95% CI, 1.10 to 6.54; p=0.051 [borderline significance]) ( Fig. 1A ), age (HR, 2.82; 95% CI, 1.47 to 5.40; p=0.007), histology (HR, 6.61; 95% CI, 2.44 to 17.94; p=0.006), and DSI (HR, 2.53; 95% CI, 1.32 to 4.87; p=0.007) were independent adverse prognostic factors for RFS ( Table 4 ).