Analysis of long-range interactions in primary human cells identifies cooperative CFTR regulatory elements.

Nucleic Acids Res · 2016 · PMC4824072 · PMID 26615198

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may be significantno p-value reported

As synonymous substitutions may be significant factors in CF ( 70 ), genetic alterations within remote regions could lead to CFTR dysregulation, which might explain discrepancy in phenotypic features of CF and CFTR -related disorders.

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