Coherent with our findings, the reduction of CARM1 levels resulted in a ∼4.6-fold increase in the Uspl1 E2- mRNA half-life compared to CTRL conditions (Figure 2G , H ), although these results did not quite reach statistical significance.
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A novel role for CARM1 in promoting nonsense-mediated mRNA decay: potential implications for spinal muscular atrophy.
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