For multiple testing correction, the calculated Meff of 1.75 [ 34 ] led to a corrected p value of 0.05, which reaches near significance.
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Association of REL polymorphisms and outcome of patients with septic shock.
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The sentences
It is important to consider that after correction for multiple testing, our result only reached near significance. Šidák/Bonferroni correction assumes, however, that markers are independent, whereas the SNPs studied here are in LD and are therefore not truly independent from each other.