Barely Significant
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Overexpression of a glucokinase point mutant in the treatment of diabetes mellitus.

Gene Ther · 2016 · PMC4827006 · PMID 26752353

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a decreasing trendno p-value reported
Then, there was a decreasing trend revealed in days 7, 14, 21 and 28, which was in accordance with an increasing blood glucose level in the mGCK group and no treatment effect in the mGCK vector group.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.