Systemic and Topical Use of Tranexamic Acid in Spinal Surgery: A Systematic Review.

Global Spine J · 2016 · PMC4836933 · PMID 27099820

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highly significantno p-value reported

tTXA-related reduction in blood loss was highly significant in both types of surgery as well as in otolaryngologic surgery (2 RCTs, n = 456 patients) and spinal surgery (2 RCTs, n = 130 patients), resulting in an overall reduction of blood loss by 29% in tTXA-treated patients.

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