Advances in neonatal screening for primary immune deficiencies.

Exp Ther Med · 2016 · PMC4840582 · PMID 27168770

Europe PMC DOI

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an increasing trendno p-value reported

In developed countries, the birth rate of premature newborns is 5–12% with an increasing trend, posing concern for newborn screening programs in particular and for public healthcare systems in general.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.