Importance of Implantable Cardioverter-Defibrillator Back-Up in Cardiac Resynchronization Therapy Recipients: A Systematic Review and Meta-Analysis.

2 , 39 Compared with medical treatment alone, CRT treatment associated with a significant 10% decrease in the absolute risk of death in the CARE‐HF trial 2 and a marginally significant 4% decrease in the absolute risk of death in the COMPANION trial. 1 A previous meta‐analysis suggested that CRT alone compared with optimal medical therapy could reduce all‐cause mortality by lowering heart failure mortality but not SCD. 40 However, data from the 8‐month extension phase of the Card

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