highly significantp = 0.00311
Among these miRNAs, downregulation of miRNA-215 expression was highly significant in the STOP-IM group (plasma miRNAs, p = 0.00311 ( Table S1 ); exosomal miRNAs, p = 0.00039 ( Table S2 )); therefore, we concluded that plasma miR-215 expression mirrors exosomal miRNA expression and focused on expression of this miRNA for further study. 2.2.