Identification of four novel susceptibility loci for oestrogen receptor negative breast cancer.

Nat Commun · 2016 · PMC4853421 · PMID 27117709

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closest p · 0.0× alpha

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highly significantP <1 × 10 −6actually significant

All 157 SNPs with highly significant associations ( P <1 × 10 −6 ) in this region, were in high linkage disequilibrium with rs188686860 and rs115635831 ( r 2 >0.90), and were located proximal (Hg19: 201,717,014-201,995,860) to the CASP8 gene ( Supplementary Table 15 ).

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marginal significanceP <0.05actually significant

In total, 63 loci have shown at least marginal significance ( P <0.05) with ER-negative breast cancer.

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