In the unadjusted model, significant associations with the presence of prevalent CVD could be detected with RTL obtained from both methods, which was more pronounced and highly significant for INV-isolated DNA: OR EZ1 = 1.25 (p EZ1 = 0.0106) and OR INV = 1.32 (p INV = 2.85 × 10 −5 ) for each decrease of RTL by 0.1.
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Influence of DNA extraction methods on relative telomere length measurements and its impact on epidemiological studies.
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