Efficacy and safety of biphasic insulin aspart and biphasic insulin lispro mix in patients with type 2 diabetes: A review of the literature.

D IABETES: A N E VER-INCREASING P UBLIC H EALTH B URDEN Globally, the number of people with diabetes continues to rise year on year, providing a major challenge to public health and an enormous economic burden.[ 1 , 4 ] The International Diabetes Federation estimates 382 million people globally had diabetes in 2013, with more than 160 million from China and India alone.[ 4 ] T2D accounts for approximately 90% of all cases worldwide, and a worrying trend is the increasing diagnosis of T2D in children and adolescents.[ 5 ] In addition to economic development, rapid transitions to Western lifestyles, and increasing obesity rates,[ 4 , 6 ] other more inherent reasons might explain the escalating burden of T2D in regions such as Asia.[ 2 , 7 , 8 , 9 ,

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