Fungistatic activity of all-trans retinoic acid against Aspergillus fumigatus and Candida albicans.

Drug Des Devel Ther · 2016 · PMC4857806 · PMID 27199548

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highly significantno p-value reported

The authors documented an immunomodulatory effect of ATRA leading to a highly significant suppression of the fungi-induced expression of TNFα, IL6, and IL12 at both the transcriptional and posttranslational levels. 12 The effectiveness of ATRA and its possible toxicity can be easily monitored in the blood.

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