The utilisation of operant delayed matching and non-matching to position for probing cognitive flexibility and working memory in mouse models of Huntington's disease.

Although it appeared to be a somewhat lower level of performance asymptote in the Skinner-like configuration, perhaps reflecting the heightened learning of the preceding DMTP task, this difference failed to achieve significance ( Fig. 3 B, Accuracy; F 1,27 = 4.13, p = 0.052), nor were there any differences in the total number of trials started (Trials; Fig. 3 D, F 1,27 = 2.00, p = n.s.), which was seen in the DMTP version of the task ( Fig. 3 C, Trials initiated; F 1,27 = 34.69, p < 0.001).

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