Six Tissue Transcriptomics Reveals Specific Immune Suppression in Spleen by Dietary Polyunsaturated Fatty Acids.

PLoS One · 2016 · PMC4864434 · PMID 27166587

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highly significantno p-value reported

HFDs caused WAT to adopt a pattern similar to immune system tissues and PUFA had specific effects in SPL In order to investigate the general effect of diet across tissues, the differentially expressed genes that were highly significant ( q <1e-7), in at least one of the tested comparisons, were used to cluster all samples in a PCA plot ( Fig 2A ).

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