A systematic review of the burden of vaccine preventable pneumococcal disease in UK adults.

BMC Pulm Med · 2016 · PMC4864929 · PMID 27169895

Europe PMC DOI

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a decreasing trendno p-value reported

The figure suggests that the true incidence from 2014/15 onwards is likely to be lower than reported above due to a decreasing trend in absolute numbers with time.

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highly significantno p-value reported

This study demonstrated a highly significant reduction in all 5 additional serotypes while there were no significant reductions in the non-PCV13 serotypes [ 21 ].

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.