a nonsignificant trendP =0.06
However, in a subgroup of patients with a TG level in the upper third (≥204 mg/dL [≥2.30 mmol/L]) and an HDL-C level in the lower third (≤34 mg/dL [≤0.88 mmol/L]), there was a nonsignificant trend ( P =0.06) for reduction in cardiovascular risk. 84 Niacin Prescription strength niacin is indicated to reduce elevated total cholesterol, LDL-C, apoB, and TG levels and to increase HDL-C in patients with primary hyperlipidemia, severe hypertriglyceridemia, and mixed dyslipidemia.