An increase in activity with the PDIP46-ΔRRM was observed but this may not be significant due to the low levels of activity.
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PDIP46 (DNA polymerase δ interacting protein 46) is an activating factor for human DNA polymerase δ.
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The sentences
While the action of Pol δ in the context of its functions in replication require its interaction with PCNA, these findings are highly significant in the context of understanding the mechanism of the effects of PDIP46 on Pol δ.