Barely Significant
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Viruses are a dominant driver of protein adaptation in mammals.

Elife · 2016 · PMC4869911 · PMID 27187613

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highly significantP =0not a probability at all
The difference in dN/dS is highly significant (permutation test P =0 after 10 9 iterations; Supplementary file 1B ).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.