Gene set analysis approaches for RNA-seq data: performance evaluation and application guideline.

ared with SAM-GS, ROAST and, marginally, to KS and GSVA; (3) ROMER detects gene sets with significantly higher average gene length, as compared with all other methods, and both GSVA and ssGSEA detect gene sets with lower average gene length, as compared with other methods (respectively with low and marginal significance).

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