Normalizing the environment recapitulates adult human immune traits in laboratory mice.

Nature · 2016 · PMC4871315 · PMID 27096360

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highly significantno p-value reported

The top 400 genes up-regulated in petstore mice showed highly significant enrichment in human adult expression data, while the top 400 down-regulated genes showed enrichment in neonates.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.