Exon-focused genome-wide association study of obsessive-compulsive disorder and shared polygenic risk with schizophrenia.

26 A recent meta-analysis, including 3007 samples from 34 studies, estimated a prevalence of OCD in schizophrenia spectrum disorders of 12.1% (95% CI=7.0–17.1%), although there were a highly significant heterogeneity among studies. 4 This heterogeneity may be considered an evidence of the difficulties in the study of OCD–schizophrenia co-occurrence.

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