PBDE flame retardants, thyroid disease, and menopausal status in U.S. women.

(2008) conducted a study of 405 adult male sport fish consumer and observed a positive trend between free T 4 and PBDE serum levels [ 61 ].

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In fully-adjusted, survey-weighted logistic regression models we found that women in the highest quartile of serum concentrations for BDE 47, 99, 100 and ΣBDE, had a greater odds of currently having a thyroid problem, compared to women in the lower quartiles of serum concentrations (Table 2 ); statistically significant associations were observed for BDE 47 (OR: 1.48; 95 % CI: 1.05–2.09), BDE 99 (OR: 1.78; 95 % CI: 1.16–2.75) and ΣBDE (OR: 1.61; 95 % CI: 1.1–2.4), and marginally significant for BDE 100 (OR: 1.50; 95 % CI: 0.97–2.31).

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