An increasing trend was observed in the appearance of the hypodiploid sub-G 1 /G 0 phase, with increasing CPRE concentration, indicative of DNA damage and cell death.[ 32 ] Pretreatment of OAW42 and OVCAR3 with CPRE augmented the cytotoxic effect of subsequent doxorubicin hydrochloride treatment.
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Effect of Procyanidin-rich Extract from Natural Cocoa Powder on Cellular Viability, Cell Cycle Progression, and Chemoresistance in Human Epithelial Ovarian Carcinoma Cell Lines.
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