Prevnar 7 Childhood Immunization Program and Serotype Replacement: Changes in Pneumococcal Incidence and Resulting Impact on Health Care Costs in Alberta (2003-2008).

We also excluded non-PCV7 serotypes for which changes in frequency did not appear to be related to PCV7 vaccine introduction (i.e., they exhibited a decreasing trend before vaccine introduction or maintained a constant incidence rate throughout the time period).

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