Endocytosis and Endosomal Trafficking of DNA After Gene Electrotransfer In Vitro.

Highly significant declines in gene expression were measured for any drug concentration of MβCD: relative to control cells, fewer than half of treated cells expressed the EGFP reporter protein (37% at 5 μmol/l MβCD, Figure 1a ), and among those, the transfection level fell to 50% ( Figure 1b ).

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