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Trends in vital signs and routine biomarkers in patients with sepsis during resuscitation in the emergency department: a prospective observational pilot study.

BMJ Open · 2016 · PMC4885278 · PMID 27225646

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an increasing trendno p-value reported
The use of paracetamol prior to ED presentation led to an increasing trend in body temperature, perhaps while the antipyretic effect of paracetamol has worn off during the patient's stay in the ED.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.