In summary, despite a more limited evidence base compared to adults, this systematic review based on study data from a >20-year period shows an overall trend of reduced incidence and prevalence for most OIs after ART initiation, and the substantial potential impact and cost savings on OIs averted with earlier ART initiation.
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Incidence and Prevalence of Opportunistic and Other Infections and the Impact of Antiretroviral Therapy Among HIV-infected Children in Low- and Middle-income Countries: A Systematic Review and Meta-analysis.
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