Homocysteine activates T cells by enhancing endoplasmic reticulum-mitochondria coupling and increasing mitochondrial respiration.

Protein Cell · 2016 · PMC4887324 · PMID 26856873

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a slight trendno p-value reported

HHcy increased both basal and maximal OCR, from 49 ± 8 pmol/min in control cells to 90 ± 12 pmol/min in HHcy treated cell for basal OCR and 70 ± 10 pmol/min to 120 ± 9 pmol/min for maximal OCR, while the ATP-coupled OCR was not altered, although with a slight trend of increase (Fig. 1 C).

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