Depletion of Histone Demethylase Jarid1A Resulting in Histone Hyperacetylation and Radiation Sensitivity Does Not Affect DNA Double-Strand Break Repair.

PLoS One · 2016 · PMC4890786 · PMID 27253695

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highly significantp < 0.0001actually significant

We observed a moderate, but highly significant sensitization of cells after Jarid1A depletion with siRNAs A1+A3 as compared to untransfected (p < 0.0001) and control-transfected (p = 0.0025) cells ( Fig 4 ).

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