The miR-9/137-CUL4A-Hippo signaling axis we have described here may have important clinical implications, since we also observed highly significant correlations among miR-9/137, CUL4A and YAP in GC tissue samples.
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Cullin 4A (CUL4A), a direct target of miR-9 and miR-137, promotes gastric cancer proliferation and invasion by regulating the Hippo signaling pathway.
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