Because of rifaximin's small effect size and the large number of OTUs for which we had to correct for multiple hypothesis testing, tests for the effect of study arm interacting with time trend toward significance at the OTU level did not reach a 10% FDR threshold.
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Effects of Rifaximin on Transit, Permeability, Fecal Microbiome, and Organic Acid Excretion in Irritable Bowel Syndrome.
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