We began with de novo motif discovery on the full set of Hsf1-binding sites (200 bp spanning the summit of 104 Hsf1-TAP ChIP-seq peaks) and identified one highly significant consensus sequence ( E -value=1.5e−164) ( Fig. 2a ).
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Hsf1 and Hsp90 orchestrate temperature-dependent global transcriptional remodelling and chromatin architecture in Candida albicans.
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