Strikingly, a highly significant reduction in the proportion of axon tips enriched for GFP-APCΔK was found when compared to GFP-APC (72.7% reduction: Fig. 4b ,c).
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Tumour Suppressor Adenomatous Polyposis Coli (APC) localisation is regulated by both Kinesin-1 and Kinesin-2.
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