Characterizing redescriptions using persistent homology to isolate genetic pathways contributing to pathogenesis.

Blocks that appear in multiple descriptors horizontally across the plot in the two-way hierarchical clustering may be significant, and correspond to some S ( r ) for r ∈ R .

also in 13,097 other papers

The relationship of this cluster to the DxHT cluster explored is also informative: they are distinct, and some SNPs more strongly associate with the complex DxHT phenotype than the simple phenotype. SNPs rs6693954 and rs1133323 show a highly significant protective association against the simple T2D, but the compound phenotype shows a weaker association.

also in 132,142 other papers