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Understanding flucloxacillin prescribing trends and treatment non-response in UK primary care: a Clinical Practice Research Datalink (CPRD) study.

J Antimicrob Chemother · 2016 · PMC4896409 · PMID 27090629

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an overall trendno p-value reported
There was significant seasonal variation with the highest prescribing rates in the summer months and the lowest rates in the winter, and an overall trend of increasing prescribing over the study period.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.