highly significantp < 0.001
Four mutations (p.Pro557Arg, p.Tyr647Ser, p.Gly815Arg, p.Phe817Leu) resulted in a highly significant reduction of agonist Imax values ( p < 0.001, n = 5–9; figure e-2a).
Four mutations (p.Pro557Arg, p.Tyr647Ser, p.Gly815Arg, p.Phe817Leu) resulted in a highly significant reduction of agonist Imax values ( p < 0.001, n = 5–9; figure e-2a).