Barely Significant
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Early breast cancer screening using iron/iron oxide-based nanoplatforms with sub-femtomolar limits of detection.

Beilstein J Nanotechnol · 2016 · PMC4901534 · PMID 27335730

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a positive trendno p-value reported
Except for MMP9 and uPA, all enzymes display a positive trend with an increasing signal for higher cancer stages.

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highly significantno p-value reported
Highly significant differences between cancer patients and healthy control group are achieved with cathepsin B and L, uPA, MMP1 and 9.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.