Comparison of diagnostic capability of macular ganglion cell complex and retinal nerve fiber layer among primary open angle glaucoma, ocular hypertension, and normal population using Fourier-domain optical coherence tomography and determining their functional correlation in Indian population.

Differences in RNFL and GCC parameters between normal and glaucomatous eyes, OHT, and POAG were highly significant ( P = 0.00, P < 0.001).

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Structural changes precede the development of optic nerve head cupping and visual field loss.[ 4 , 5 , 6 , 7 , 8 , 9 ] Changes in nerve fiber layer thickness of 20 μ may be significant interval changes in glaucoma.[ 10 ] Optical coherence tomography (OCT) provides objective, quantitative, and reproducible measurements of the ganglion cell complex (GCC) and retinal nerve fiber layer (RNFL) thickness.[ 11 ] Fourier-domain (FD)-OCT has resolution power up to 5 μ in measuring the ave

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